Clinical trials
TALENTOP trial: conversion surgery in advanced HCC
The TALENTOP study, a multicentre, open-label, randomised phase 3 trial, compares liver resection after atezolizumab and bevacizumab with maintenance therapy in patients with locally advanced hepatocellular carcinoma. The study is discussed in a comment by Fornera et al. in The Lancet, highlighting the evolving role of immunotherapy and conversion surgery in advanced HCC.